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Fenugreek (Trigonella foenum-graecum)



Depletions

Fenugreek/Nutrient Depletion:
  • Blood glucoseBlood glucose: Data from preclinical and human study suggest that fenugreek possesses both acute and chronic hypoglycemic properties (77; 78; 79; 80; 81; 82; 80; 75; 83; 84; 85; 86; 87; 88; 89; 90; 76; 91; 92; 93; 94; 80; 95).
  • CalciumCalcium: Fenugreek contains insoluble oxalates, which may bind calcium, reducing its intestinal availability (230).
  • IronIron: Based on human study, frequent consumption of fenugreek was associated with high prevalence of anemia (214). Fenugreek may act as an iron absorption inhibitor. Also, in vitro, although addition of fenugreek to a cereal meal increased iron content, available iron was decreased (265).
  • LipidsLipids: Based on human (93; 127; 128), animal, and in vitro study (129; 130; 131; 132; 133; 134; 135; 136; 137; 138; 139; 115; 140; 141; 142; 143; 144; 145; 42; 146; 114; 147; 148; 149; 145) and review (150; 151; 55), fenugreek may lower triglycerides, total cholesterol, and low-density lipoprotein (LDL) levels, and increase HDL cholesterol. Based on human study, consumption of fenugreek seeds resulted in decreased fat intake (202).
  • PotassiumPotassium: A fenugreek aqueous extract was found to reduce potassium levels by 14% in human study and may precipitate hypokalemia when used with some diuretics, laxatives, mineralocorticoids, or other hypokalemic agents (83).
  • Vitamin EVitamin E: Addition of fenugreek seeds to the diet of diabetic rats decreased alpha-tocopherol levels (223).

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The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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