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Related terms
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    Related terms
    • U.S. Brand Names: PriLOSEC OTC® [OTC];PriLOSEC®
    • Canadian Brand Names: Apo-Omeprazole®;Losec®;Mylan-Omeprazole;PMS-Omeprazole;PMS-Omeprazole DR;ratio-Omeprazole;Sandoz-Omeprazole
    • Mexican Brand Names: Aleprozil;Azoran;Domer;Inhibitron;Losec;Mopral;Olexin;Prazidec;Suifac;Ulsen;Vulcasid
    • Pharmacologic Category: Proton Pump Inhibitor;Substituted Benzimidazole

    • It is used to stop or treat GI (gastrointestinal) ulcers caused by infection.
    • It is used to treat gastroesophageal reflux disease.
    • It is used to treat heartburn.
    • It is used to treat syndromes caused by lots of stomach acid.
    • It is used to stop or treat ulcers of the swallowing tube (esophagus).
    • Omeprazole helps avoid harm to the GI (gastrointestinal) tract caused by stomach acid or infection.


    How to take

    • All products:
    • Take 1 hour before the first meal of the day.
    • Tablet (Prilosec OTCT):
    • Swallow tablet whole. Do not chew, break, or crush.
    • Do not use for more than 14 days. Talk with your doctor.
    • Capsule:
    • Swallow capsule whole. Do not chew, break, or crush.
    • You may sprinkle contents of capsule on soft food or liquid. Do not chew.
    • For patients who have feeding tubes, open the capsule and mix with 3 tablespoonfuls of apple juice. Give in the feeding tube. Flush the feeding tube before and after this drug is given.
    • Packets:
    • Mix the 2.5 mg packet contents with 1 teaspoon of water or the 10 mg packet contents with 1 tablespoon of water. Let sit for 2 to 3 minutes, stir, and drink. Rinse cup with more water and drink.
    • Those who have feeding tubes can also use the liquid. Flush the feeding tube before and after this drug is given.

    Missed Dose

    • Take a missed dose as soon as you think about it.
    • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
    • Do not take two doses or extra doses.
    • Do not change the dose or stop this drug. Talk with the doctor.


    • Store at room temperature.
    • Protect capsules from light.
    • Protect capsules and tablets from water. Do not store in a bathroom or kitchen.



    • Unsafe reactions may happen. This drug cannot be taken while you are taking some other drugs. Check all the drugs you are taking with your doctor.


    • If you have an allergy to omeprazole or any other part of this drug.
    • Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.


    • If you have liver disease, talk with your doctor.
    • Use care if you have risks for soft, brittle bones called osteoporosis (alcohol use, cigarette smoking, other family members with brittle bones, taking drugs to treat seizures, taking steroids).
    • Check all drugs you are taking with your doctor. This drug may not mix well with some other drugs.
    • Avoid beer, wine, or liquor.
    • Tell your doctor if you are pregnant or plan on getting pregnant.
    • Tell your doctor if you are breast-feeding.

    Side Effects

    • Headache.
    • Upset stomach or throwing up. Many small meals, good mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Loose stools.
    • Hip, spine, or wrist fractures may rarely happen.


    • Change in the health problem being treated. Is it better, worse, or about the same?
    • Follow up with the doctor.

    Contact a healthcare provider

    • If you think there was an overdose, call your local poison control center or ER right away.
    • Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; seizures; or swelling of face, lips, tongue, or throat.
    • Very bad dizziness or passing out.
    • A fast heartbeat.
    • Very bad belly pain.
    • Very loose stools.
    • Very upset stomach or throwing up.
    • Any bruising or bleeding.
    • Very bad bone pain.
    • Very bad muscle pain or weakness.
    • Seizures.
    • Any rash.
    • Health problem is not better or you are feeling worse.

    General Statements

    • If you have a very bad allergy, wear an allergy ID at all times.
    • Do not share your drugs with others and do not take anyone else's drugs.
    • Keep all drugs out of the reach of children and pets.
    • Most drugs can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada, take any unused drugs to the pharmacy. Also, visit http://www.hc-sc.gc.ca/hl-vs/iyh-vsv/med/disposal-defaire-eng.php#th to learn about the right way to get rid of unused drugs.
    • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
    • Call your doctor for help with any side effects. You may also call the FDA at 1-800-FDA-1088 or Health Canada's Vigilance Program at 1-866-234-2345.
    • Talk with the doctor before starting any new drug, including OTC, natural products, or vitamins.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (www.naturalstandard.com)

    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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