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Table of Contents > Health Dictionary > Neuroaxonal dystrophy

Neuroaxonal dystrophy

A rare disorder that begins in the second year of life and is relentlessly progressive; clinically characterized initially by walking difficulties, weakness, and areflexia, later followed by corticospinal and pseudobulbar findings, blindness, loss of pain appreciation, and mental deterioration; pathologically, eosinophilic spheroids of swollen axoplasm are found in various central nuclei; autosomal recessive inheritance.
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